Gene description for AP2A1
Gene name	adaptor related protein complex 2 subunit alpha 1
Gene symbol	AP2A1
Other names/aliases	ADTAA AP2-ALPHA CLAPA1
Species	Homo sapiens
Experiment description of studies that identified AP2A1 in Glioblastoma cells
1 Experiment ID 723 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25802036    Organism Homo sapiens Experiment description Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Authors de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. Journal name Int J Cancer Publication year 2015 Sample Glioblastoma cells Sample name GS184 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150064: EV-METRIC:0%, 0%, 29%
2 Experiment ID 1242 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25261722    Organism Homo sapiens Experiment description Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Authors Kore RA, Abraham EC. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Glioblastoma cells Sample name U373 cells treated with 10ng/ml of IL-1. Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140183: EV-METRIC:22%